WATCH: Colorado football pre-game from Jones AT&T Stadium in Lubbock

What's happening?

The Colorado Buffaloes are set to take on the No. 23 Texas Tech Red Raiders in Lubbock on Saturday night. The game will be televised on FS1.

The Buffaloes are coming off a 49-7 loss to TCU last week, which dropped them to 0-5 on the season. The Red Raiders are coming off a 34-27 win over West Virginia.

This will be the first meeting between the two schools since 2010.

Who are the key players?

For Colorado, quarterback Brendon Lewis will be making his second start. He threw for 155 yards and a touchdown against TCU.

Running back Deion Smith is averaging 6.2 yards per carry this season. He has scored three touchdowns in five games.

On defense, linebacker Robert Barnes leads the team with 40 tackles. He also has 2.5 sacks and an interception.

For Texas Tech, quarterback Donovan Smith is averaging 300.8 passing yards per game. He has thrown for 10 touchdowns and four interceptions.

Running back SaRodorick Thompson is averaging 5.1 yards per carry this season. He has scored six touchdowns in five games.

On defense, linebacker Krishon Merriweather leads the team with 36 tackles. He also has 2.5 sacks and two interceptions.

What's at stake?

For Colorado, this game is a chance to get their first win of the season. A win over a ranked opponent would also give them some momentum heading into the rest of the season.

For Texas Tech, this game is a chance to improve to 6-0 on the season. A win over Colorado would also give them a leg up in the Big 12 standings.

Prediction

The Red Raiders are a heavy favorite in this game. They are a more talented team, and they are playing at home.

However, the Buffaloes have a chance to pull off an upset if they can play mistake-free football. They will need to be able to run the ball effectively and protect the football on offense.

On defense, the Buffaloes will need to be able to generate pressure on Smith and force turnovers.

Ultimately, I predict that the Red Raiders will win the game, but the Buffaloes will keep it close.